PLXNA2 Antibody

1. although plexin-A4 overexpression restored Sema3A signaling in plexin-A1-silenced cells, it failed to restore Sema3B signaling in plexin-A2-silenced cells. PMID: 25335892
2. PLXNA2 upregulation contributes to TMPRSS2:ERG-mediated enhancements of PC3c cell migration and invasion. PMID: 23708657
3. PLXNA2 has been identified as a new rare copy number variations gene for tetralogy of Fallot. PMID: 22912587
4. results of our study reveal that PlxnA2 has a pro-osteogenic function by modulating BMP2 signaling PMID: 22095611
5. PLXNA2 polymorphisms show association with ankylosing spondylitis. PMID: 22011406
6. in vitro analysis of PLXNA2 revealed that the gene has higher expression in more aggressive breast cancer cell types. PMID: 21925246
7. An association is identified between variants in the PLXNA2 gene and schizophrenia in two collections of schizophrenia cases and controls. High-density SNP mapping showed that the region of association spans approximately 60 kb of the PLXNA2 gene. PMID: 16402134
8. results suggest that PLXNA2 may not play a major role in the development of schizophrenia in our Japanese sample PMID: 17346868
9. PLXNA2 confers a varying genetic risk for schizophrenia among different populations. PMID: 18065206
10. Analysis of 3 SNPs at the PLXN A2 locus; we failed to replicate previously reported association of this locus and schizophrenia. PMID: 18096369
11. mutations in GATA6 are genetic causes of congenital heart diseases involving outflow tract defects, as a result of the disruption of the direct regulation of semaphorin 3C-plexin A2 signaling PMID: 19666519

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HGNC: 9100

OMIM: 601054

KEGG: hsa:5362

STRING: 9606.ENSP00000356000

UniGene: Hs.497626