PTPN9 Antibody, Biotin conjugated

1. Results from a study on gene expression variability markers in early-stage human embryos shows that PTPN9 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
2. this study highlights an important role for miR-96 in the regulation of PTPN9 in breast cancer cells and may provide insight into the molecular mechanisms of breast carcinogenesis. PMID: 27857177
3. Expression of MEG2 is reversely correlated with that of miR-181a-5p in gastric cancer. PMID: 28747184
4. PTPN9 inhibited cell proliferation in HepG2 cells. PMID: 26715439
5. PTPMeg2 is an important phosphatase for the dephosphorylation of STAT3 and plays a critical role in breast cancer development. PMID: 22394684
6. This study indentified VEGFR2 as a PTPN9 substrate, and indicated that PTPN9 is a negative regulator of VEGFR2 signaling and function in endothelial cells. PMID: 22763125
7. data suggest PTPN9 as a negative regulator of breast cancer cells by targeting ErbB2 and EGFR and inhibiting STAT activation PMID: 20335174
8. Purification and characterization of protein tyrosine phosphatase PTP-MEG2 PMID: 12112018
9. PTP-MEG2 has an important role in the development of erythroid cells. PMID: 12920026
10. PTPase-MEG2 through its Sec14p homology domain couples inositide phosphorylation to tyrosine dephosphorylation and the regulation of intracellular traffic of the secretory pathway in T cells. PMID: 14662869
11. PTP-MEG2 reduced the phosphotyrosine content of NSF and co-localized with NSF and syntaxin 6 in intact cells, the first demonstrated role for a protein tyrosine phosphatase in the regulated secretory pathway PMID: 15322554
12. role in the negative regulation of hepatic insulin signaling PMID: 16679294
13. the N terminus of PTPMEG2 is necessary for the targeting of this phosphatase to the secretory vesicle compartment by association with other proteins involved in intracellular transport. PMID: 17387180

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HGNC: 9661

OMIM: 600768

KEGG: hsa:5780

STRING: 9606.ENSP00000303554

UniGene: Hs.445775