SLC35A2 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA021584LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLC35A2 Polyclonal antibody

Uniprot No.

P78381

Target Names

SLC35A2

Alternative Names

SLC35A2 antibody; UGALT antibody; UGT antibody; UGTL antibody; UDP-galactose translocator antibody; Solute carrier family 35 member A2 antibody; UDP-galactose transporter antibody; UDP-Gal-Tr antibody; UGT antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human UDP-galactose translocator protein (136-234AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.

Gene References into Functions

The short N-terminal region composed of 35 N-terminal amino-acid residues of UGT was crucial for galactosylation of N-glycans. PMID: 25451267
UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
De novo mutations in SLC35A2 encoding a UDP-galactose transporter cause early-onset epileptic encephalopathy. PMID: 24115232
The data further supports the hypothesis that UGT and NGT cooperate in the UDP-Gal delivery for glycosyltransferases located in the Golgi apparatus. PMID: 23583405
Mosaicism of the UDP-galactose transporter SLC35A2 causes a congenital disorder of glycosylation. PMID: 23561849
localization of the UDP-Gal transporter may depend on the presence of the partner splice variant PMID: 21918738

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Involvement in disease

Congenital disorder of glycosylation 2M (CDG2M)

Subcellular Location

Golgi apparatus membrane; Multi-pass membrane protein.

Protein Families

Nucleotide-sugar transporter family, SLC35A subfamily

Database Links

HGNC: 11022

OMIM: 300896

KEGG: hsa:7355

STRING: 9606.ENSP00000247138

UniGene: Hs.21899

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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