STK25 Antibody

Code CSB-PA022842LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA022842LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA022842LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) STK25 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
C86992 antibody; Serine/threonine kinase 25 antibody; Serine/threonine kinase 25 (STE20 homolog, yeast) antibody; Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a antibody; Serine/threonine kinase 25 (yeast) antibody; Serine/threonine protein kinase 25 antibody; Serine/threonine-protein kinase 25 antibody; SOK 1 antibody; SOK-1 antibody; SOK1 antibody; Ste20 like kinase antibody; Ste20 yeast homolog antibody; Ste20-like antibody; STE20-like kinase antibody; Ste20/oxidant stress response kinase 1 antibody; Sterile 20 (oxidant stress response kinase 1) antibody; Sterile 20/oxidant stress-response kinase 1 antibody; STK25 antibody; STK25_HUMAN antibody; Yeast Sps1/Ste20 related kinase 1 antibody; YSK 1 antibody; YSK1 antibody
Raised in
Species Reactivity
Recombinant Human Serine/threonine-protein kinase 25 protein (1-426AA)
Immunogen Species
Homo sapiens (Human)

The STK25 Antibody (Product code: CSB-PA022842LA01HU) is Non-conjugated. For STK25 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA022842LB01HU STK25 Antibody, HRP conjugated ELISA
FITC CSB-PA022842LC01HU STK25 Antibody, FITC conjugated
Biotin CSB-PA022842LD01HU STK25 Antibody, Biotin conjugated ELISA
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.
Gene References into Functions
  1. STK25 regulates lipid partitioning in human liver cells by controlling TAG synthesis as well as lipolytic activity and thereby NEFA release from lipid droplets for beta-oxidation and TAG secretion. PMID: 26553096
  2. Our results suggest that MST4, STK25 and PDCD10 are upregulated in prostate cancer and may play roles in prostate tumorigenesis. PMID: 25550858
  3. This review notes that all 3 human germinal center kinase III genes consist of 12 exons and are ubiquitously expressed. In SOK1 and MST4, exon 1 encodes a 5' untranslated region, but this is not the case for MST3. PMID: 23889253
  4. Down-modulation of STK25, but not STK24, rescued medulloblastoma cells from NGF-induced TrkA-dependent cell death, suggesting that STK25 is part of the death-signaling pathway initiated by TrkA and CCM2. PMID: 22782892
  5. PDCD10 might be a regulatory adaptor required for STK25 functions, which differ distinctly depending on the redox status of the cells that may be potentially related to tumor progression. PMID: 22652780
  6. Significantly higher STK25 levels were observed in the skeletal muscle of type 2 diabetic patients, compared with individuals with normal glucose tolerance. PMID: 22391949
  7. The results of the study results indicate that attenuation of SOK1 enhanced cell migration and lead to changes in the expression of migration-associated proteins such as FAK and GM130. PMID: 21396913
  8. In cultured human endothelial cells, CCM3 and STK25 regulated barrier function in a manner similar to CCM2, and STKs negatively regulated Rho by directly activating moesin. PMID: 20592472
  9. 14-3-3zeta is a specific substrate for YSK1 that localizes to the Golgi apparatus, and potentially links YSK1 signaling at the Golgi apparatus with protein transport. PMID: 15037601
  10. Ste20 family member (MAP4K3) that is required for maximal S6K (S6 kinase)/4E-BP1 [eIF4E (eukaryotic initiation factor 4E) that is required for maximal S6K (S6 kinase). PMID: 17253963
  11. SOK1 entry into the nucleus is important for the cell death response PMID: 18364353

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Subcellular Location
Cytoplasm. Golgi apparatus. Note=Localizes to the Golgi apparatus.
Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
Tissue Specificity
Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.
Database Links

HGNC: 11404

OMIM: 602255

KEGG: hsa:10494

STRING: 9606.ENSP00000325748

UniGene: Hs.516807

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