SV2A Antibody

1. Botulinum neurotoxin type A inhibits synaptic vesicle 2 expression in breast cancer cell lines. PMID: 26339411
2. SV2A expression in the bladder urothelium increases after BoNT-A injection. PMID: 26241848
3. the way LEV analogues may interact with SV2A PMID: 25692762
4. agents that act on the conformation of SV2A might hold great potential in the search for new SV2A-based anticonvulsant therapies PMID: 23530581
5. The newly identified galactose transport capability of SV2A may have an important role in regulating/modulating synaptic function. PMID: 25326386
6. The SV2A/FE65 interaction might play a role in synaptic signal transduction. PMID: 24284412
7. In classical mesial temporal sclerosis 1A, the expression of SV2 isoforms is altered with a marked decrease of SV2A paralleling synaptic loss. PMID: 23617838
8. High SV2A expression is associated with breast cancer. PMID: 23244111
9. This study in the German population provides evidence, at a genetic level, for the involvement of the SV2A gene region in schizophrenia. PMID: 23017826
10. Data report a combined modelling and mutagenesis study that successfully identifies another 11 residues in synaptic vesicle protein 2A that appear to be involved in ligand binding. PMID: 21936812
11. expression of SV2A in tumor and peritumoral tissue is correlated to the clinical response to levetiracetam and predicts levetiracetam efficacy PMID: 21795655
12. the role of SV2A in epileptogenesis in patients with glial tumors is questionable PMID: 20167814
13. We found no association between genetic variation in SV2A and response to levetiracetam or epilepsy predisposition PMID: 18977120
14. The pattern of SV2A immunoreactivity with reduced neuropil expression and altered cellular and subcellular distribution suggests a possible contribution of SV2A to the epileptogenicity of these malformations of cortical development. PMID: 19220410
15. Botulinum toxin type A (BTA) inhibits the growth of LNCaP human PCa cells in vitro and in vivo. BTA acts on the cells by virtue of the BTA receptor, the SV2 protein. PMID: 19399787

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HGNC: 20566

OMIM: 185860

KEGG: hsa:9900

STRING: 9606.ENSP00000358142

UniGene: Hs.516153