TSPAN14 Antibody, HRP conjugated

Code CSB-PA847712LB01HU
Size US$299
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TSPAN14 Polyclonal antibody
Uniprot No. Q8NG11
Target Names TSPAN14
Alternative Names
TSPAN14; TM4SF14; Tetraspanin-14; Tspan-14; DC-TM4F2; Transmembrane 4 superfamily member 14
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Tetraspanin-14 protein (114-215AA)
Immunogen Species Homo sapiens (Human)
Conjugate HRP
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Negatively regulates ADAM10-mediated cleavage of GP6. Promotes ADAM10-mediated cleavage of CDH5.
Gene References into Functions
  1. Data suggest that large extracellular loop of Tspan14 mediates interaction with ADAM10, promotes ADAM10 maturation/trafficking to cell surface, and affects ADAM10 substrate specificity; ADAM10/Tspan14 interact in platelets/vascular endothelial cells. PMID: 26668317
  2. genetic alterations of TSPAN14, SLC2A13 and PHF20 could play a role in non-small-cell lung cancer promotion PMID: 19473719
Subcellular Location Cell membrane; Multi-pass membrane protein.
Protein Families Tetraspanin (TM4SF) family
Database Links

HGNC: 23303

KEGG: hsa:81619

STRING: 9606.ENSP00000361229

UniGene: Hs.718943

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