ZBTB20 Antibody

1. ZBTB20 knockdown inhibited glioblastoma cell proliferation, migration, and invasion. PMID: 30099442
2. High ZBTB20 expression is associated with hepatocellular carcinoma. PMID: 26893361
3. We report a boy with intellectual disability carrying two de novo missense mutations in the last exon of ZBTB20 (Ser616Phe and Gly741Arg; both previously unreported). One of them, Ser616Phe, affects an amino acid located in one of the C2H2 zing-fingers involved in DNA-binding and close to other missense mutations already described. Reverse phenotyping showed that this patient presents with classic features of Primrose syn PMID: 27061120
4. ZBTB20 rs9841504 polymorphism is a protective factor for gastric cancer rather than esophageal cancer. PMID: 27646774
5. 3q13.31 microdeletion-based dosage imbalance of ZBTB20 linked to a range of neurodevelopmental, cognitive and psychiatric disorders, likely mediated by dysregulation of multiple ZBTB20 target genes. PMID: 25062845
6. Major depressive disorder is associated with significant hypermethylation within the coding region of ZBTB20. PMID: 24694013
7. important role for ZBTB20 in controlling NSCLC development PMID: 25311537
8. Missense mutations in ZBTB20 underlie Primrose syndrome. PMID: 25017102
9. This study disclosed Zbtb20-mediated transcriptional repressor mechanism may be involved in development of the human archicortex. PMID: 23283686
10. Polymorphism in ZBTB20 gene is associated with gastric cancer. PMID: 23861218
11. We identified new susceptibility loci for non-cardia gastric cancer at 3q13.31: rs9841504 in ZBTB20 PMID: 22037551
12. ZBTB20 mRNA & protein expression were elevated significantly in HCC tissues compared with the paired non-tumor tissues & normal liver. HCC recurrence or metastasis increased & disease-free survival decreased with high ZBTB20 expression. PMID: 21702992
13. Misexpression of Zbtb20 in transgenic mice converts the normal cytoarchitectonic organization of the subiculum, postsubiculum, and granular retrosplenial cortex to a CA1-like stratum pyramidale. PMID: 19955470

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HGNC: 13503

OMIM: 259050

KEGG: hsa:26137

STRING: 9606.ENSP00000419153

UniGene: Hs.202577