Recombinant Human Beta-galactoside alpha-2,6-sialyltransferase 2 (ST6GAL2), partial

Code CSB-YP846644HU
MSDS
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Source Yeast
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Code CSB-EP846644HU
MSDS
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Source E.coli
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Code CSB-EP846644HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP846644HU
MSDS
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Source Baculovirus
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Code CSB-MP846644HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
ST6GAL2
Uniprot No.
Alternative Names
6-sialyltransferase 2; 6-ST 2; Alpha 2; Alpha 2,6 ST 2; beta galactoside alpha 2,6 sialyltransferase II; Beta-galactoside alpha-2; CMP N acetylneuraminate beta galactosamide alpha 2,6 sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2; EC 2.4.99.1; FLJ30711; FLJ37730; FLJ38334; hST6Gal II; KIAA1877; Sialyltransferase 2; SIAT2; SIAT2_HUMAN; ST6 beta galactosamide alpha 2,6 sialyltranferase 2; ST6Gal II; ST6GAL2; ST6GalII
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids.
Gene References into Functions
  1. This suggests that ST6GAL2 transcription could be potentially activated for specific neuronal functions. PMID: 19768537
  2. identification and expression and localization in brain PMID: 12603328
Subcellular Location
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 29 family
Tissue Specificity
Weakly expressed in some tissues, such as small intestine, colon and fetal brain.
Database Links

HGNC: 10861

OMIM: 608472

KEGG: hsa:84620

STRING: 9606.ENSP00000355273

UniGene: Hs.98265

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