Product Details

Purity

≥ 85% as determined by SDS-PAGE.

Activity

Not Test

Target Names

HTN1

Uniprot No.

P15515

Research Area

Immunology

Species

Homo sapiens (Human)

Source

E.coli

Expression Region

20-57aa

Target Protein Sequence

DSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Mol. Weight

23.0 kDa

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal 6xHis-SUMO-tagged

Form

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Datasheet & COA

Please contact us to get it.

Target Background

Function

Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities.

Gene References into Functions

salivary histatin-1 is a novel proangiogenic factor that may contribute to oral wound healing PMID: 28751526
This study evaluated the effects of Hst1 on cellular barrier function. Hst1 counteracted the effects of epithelial-mesenchymal transition inducers on the outgrowth of oral cancer cell spheroids, suggesting that Hst1 affects processes that are implicated in cancer progression. PMID: 28522595
Histatin-1 is specifically expressed in human lacrimal epithelium. PMID: 26824896
Histatins are salivary proteins with antimicrobial activity. PMID: 2303595
We investigated interactions among and functions of histatin 1 and the other proteins that are present in saliva by using high-throughput mass spectrometric techniques. This led to the identification of 43 proteins able to interact with histatin 1. PMID: 23001880
inhibits calcium phosphate precipitation PMID: 12060866
The results allowed locating sulfation on the last four tyrosines (Tyr 27, 30, 34, and 36). PMID: 17503797
histatin 1 (Hst1) and histatin 2 (Hst2) as major wound-closing factors in human saliva PMID: 18650243
These findings indicate that the regulation of the histatin gene expression may be intricate, and it seems to have a cell-type preference in the salivary gland cells. PMID: 19060311

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Subcellular Location

Secreted.

Protein Families

Histatin/statherin family

Tissue Specificity

Submandibular and parotid glands.

Database Links

HGNC: 5283

OMIM: 142701

KEGG: hsa:3346

STRING: 9606.ENSP00000246896

UniGene: Hs.250959

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Code	CSB-EP010878HU
Abbreviation	Recombinant Human HTN1 protein
MSDS	MSDS Datasheet
Size	$256
	Order now
Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Recombinant Human Histatin-1 (HTN1)

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