Purity
Greater than 90% as determined by SDS-PAGE.
Alternative Names
2810473H05Rik; Acetylglucosamine phosphomutase; Agm1; AGM1_HUMAN; BB187688; C77933; DKFZp434B187; EC 5.4.2.3; FLJ11614; FLJ13623; IMD23; N acetylglucosamine phosphate mutase 1; N acetylglucosamine phosphate mutase; N-acetylglucosamine-phosphate mutase; PAGM; PGM 3; PGM3; Phosphoacetylglucosamine mutase; Phosphoglucomutase 3; Phosphoglucomutase-3
Species
Homo sapiens (Human)
Expression Region
1-542aa
Target Protein Sequence
MDLGAITKYSALHAKPNGLILQYGTAGFRTKAEHLDHVMFRMGLLAVLRSKQTKSTIGVMVTASHNPEEDNGVKLVDPLGEMLAPSWEEHATCLANAEEQDMQRVLIDISEKEAVNLQQDAFVVIGRDTRPSSEKLSQSVIDGVTVLGGQFHDYGLLTTPQLHYMVYCRNTGGRYGKATIEGYYQKLSKAFVELTKQASCSGDEYRSLKVDCANGIGALKLREMEHYFSQGLSVQLFNDGSKGKLNHLCGADFVKSHQKPPQGMEIKSNERCCSFDGDADRIVYYYHDADGHFHLIDGDKIATLISSFLKELLVEIGESLNIGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTALFSTAVEMKIKQSAEQLEDKKRKAAKMLENIIDLFNQAAGDAISDMLVIEAILALKGLTVQQWDALYTDLPNRQLKVQVADRRVISTTDAERQAVTPPGLQEAINDLVKKYKLSRAFVRPSGTEDVVRVYAEADSQESADHLAHEVSLAVFQLAGGIGERPQPGF
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Protein Length
Full Length
Tag Info
N-terminal 6xHis-SUMO-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the
glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer,
6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description
This Human PGM3 recombinant protein was produced in E.coli, where the gene sequence encoding Human PGM3 (1-542aa) was expressed with the N-terminal 6xHis-SUMO tag. The purity of this PGM3 protein was greater than 90% by SDS-PAGE.
The main function of PGM3 is to catalyze the isomerization reaction of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to N-acetylglucosamine-1-phosphate (GlcNAc-1-P). This is a chemical transformation of a substrate that is crucial for various biosynthetic and metabolic pathways. PGM3 plays a critical role in the biosynthesis of glycoproteins. Glycoproteins are a class of proteins that have specific sugar molecules attached to them, and these sugar molecules are essential for the stability and function of the proteins. The activity of PGM3 ensures the proper biosynthesis of glycoproteins.
PGM3 is also associated with the function of the immune system. Certain mutations or defects may result in impaired PGM3 function, affecting the normal functioning of immune cells. This could lead to immunodeficiency, making individuals more susceptible to infections. PGM3 deficiency or mutations may be associated with a rare genetic disorder known as PGM3 deficiency disease (PGM3-CDG). This disease can lead to various symptoms, including immune system issues, neurological problems, and growth retardation.
