Recombinant Drosophila melanogaster Putative odorant receptor 67d(Or67d)

Code CSB-CF893325DLU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. Q9VT92
Storage Buffer Tris-based buffer,50% glycerol
Species Drosophila melanogaster (Fruit fly)
Sequence MLKMAKVEPVERYCKVIRMIRFCVGFCGNDVADPNFRMWWLTYAVMAAIAFFFACTGYTI YVGVVINGDLTIILQALAMVGSAVQGLTKLLVTANNASHMREVQNTYEDIYREYGSKGDE YAKCLEKRIRITWTLLIGFMLVYIILLGLVITFPIFYLLILHQKVLVMQFLIPFLDHTTD GGHLILTAAHVILITFGGFGNYGGDMYLFLFVTHVPLIKDIFCVKLTEFNELVMKRNDFP KVRAMLCDLLVWHQLYTRMLQTTKKIYSIVLFVQLSTTCVGLLCTISCIFMKAWPAAPLY LLYAAITLYTFCGLGTLVENSNEDFLSVIYTNCLWYELPVKEEKLIIMMLAKAQNEVVLT AADMAPLSMNTALQLTKGIYSFSMMLMNYLG
Source in vitro E.coli expression system
Gene Names Or67d
Protein Names Recommended name: Putative odorant receptor 67d
Expression Region 1-391
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Plays a role in detection and sensitivity to pheromones and signal transduction of the fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA). Acts in concert with Snmp and lush to capture cVA molecules on the surface of Or67d expressing olfactory dendrites and facilitate their transfer to the odorant-receptor Orco complex. Necessary to mediate behavioral responses to cVA by regulating both male and female mating behavior. Activation of Or67d neurons by cVA inhibits courtship of other males, whereas in females their activation promotes receptivity to other males. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families Insect chemoreceptor superfamily, Heteromeric odorant receptor channel (TC 1.A.69) family, Or67d subfamily
Tissue Specificity Expressed in antenna.
Database Links

KEGG: dme:Dmel_CG14157

STRING: 7227.FBpp0076026

UniGene: Dm.27107

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