Recombinant Human Cadherin-3(CDH3)

Code CSB-CF005052HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P22223
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names CDH3
Protein Names Recommended name: Cadherin-3 Alternative name(s): Placental cadherin Short name= P-cadherin
Expression Region 108-829
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Involvement in disease Hypotrichosis congenital with juvenile macular dystrophy (HJMD); Ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS)
Subcellular Location Cell membrane, Single-pass type I membrane protein
Tissue Specificity Expressed in some normal epithelial tissues and in some carcinoma cell lines.
Database Links

HGNC: 1762

OMIM: 114021

KEGG: hsa:1001

STRING: 9606.ENSP00000264012

UniGene: Hs.191842

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