Recombinant Human Lipid phosphate phosphatase-related protein type 4(LPPR4)

Code CSB-CF770341HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. Q7Z2D5
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MQRAGSSGGRGECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVI KDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAI PFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVG VHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTV INSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQ YKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSA KNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRA NTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMR SSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEET QENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGST VSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQT YELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSI SSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
Source in vitro E.coli expression system
Gene Names PLPPR4
Protein Names Recommended name: Lipid phosphate phosphatase-related protein type 4 EC= 3.1.3.4 Alternative name(s): Brain-specific phosphatidic acid phosphatase-like protein 1 Plasticity-related gene 1 protein Short name= PRG-1
Expression Region 1-763
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus.
Subcellular Location Membrane, Multi-pass membrane protein
Protein Families PA-phosphatase related phosphoesterase family
Tissue Specificity Specifically expressed in neurons.
Database Links

HGNC: 23496

OMIM: 607813

KEGG: hsa:9890

STRING: 9606.ENSP00000359204

UniGene: Hs.13245

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