Recombinant Mouse Tyrosine-protein phosphatase non-receptor type 5(Ptpn5)

Code CSB-CF019042MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P54830
Storage Buffer Tris-based buffer,50% glycerol
Species Mus musculus (Mouse)
Sequence MCCSERLLGLPQPVEMEAPDEAEGLPSKQKEMPPPPPPSPPSEPAQKLPPQGAGSHSLTVRSSLCLFAASQFLLACGVLWLSGHGHSWLQNTTDLISSSLTVLNHLGPVAWLGSGTWGIPSLLLVSLTVSLVIVTTLVWHLLKAPPEPPAPLPPEDRRQSVSRQPSFTYSEWMEEKVEDDFLDLDAVPETPVFDCVMDIKPETDPASLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLVSPREESAHEYLLSASRVLRAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVRLTSPDPEDPLSSYINANYIRGYSGEEKVYIATQGPIVSTVADFWRMVWQERTPIIVMITNIEEMNEKCTEYWPEEQVVHDGVEITVQKVIHTEDYRLRLISLRRGTEERSLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQQLRREGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLYEKQLSLQSSE
Source in vitro E.coli expression system
Gene Names Ptpn5
Protein Names Recommended name: Tyrosine-protein phosphatase non-receptor type 5 EC= 3.1.3.48Alternative name(s): Neural-specific protein-tyrosine phosphatase Striatum-enriched protein-tyrosine phosphatase Short name= STEP
Expression Region 1-541
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
Subcellular Location Isoform STEP61: Endoplasmic reticulum membrane, Multi-pass membrane protein, SUBCELLULAR LOCATION: Isoform STEP46: Cytoplasm
Protein Families Protein-tyrosine phosphatase family, Non-receptor class subfamily
Tissue Specificity STEP20 is expressed only in the CNS.
Database Links

KEGG: mmu:19259

STRING: 10090.ENSMUSP00000033142

UniGene: Mm.4654

Pathway MAPK signaling pathway

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