Recombinant Rat Endothelin-converting enzyme 1(Ece1)

Code CSB-CF007371RA
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P42893
Storage Buffer Tris-based buffer,50% glycerol
Species Rattus norvegicus (Rat)
Sequence MGSLRPPQGLGLQWSSFFLGKKGPGLTVSLPLLASSLQVNFRSPRSGQRCWAARTSVEKRLVVLVTLLAAGLVACLAALGIQYRTRTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTASASEAEKKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEDSIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNAIFYPVEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIILEIKKAFEESLSTLKWMDEDTRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSLRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYNNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQILPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGSPMNPRHKCEVW
Source in vitro E.coli expression system
Gene Names Ece1
Protein Names Recommended name: Endothelin-converting enzyme 1 Short name= ECE-1 EC= 3.4.24.71
Expression Region 1-762
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Converts big endothelin-1 to endothelin-1.
Subcellular Location Cell membrane, Single-pass type II membrane protein
Protein Families Peptidase M13 family
Tissue Specificity All isoforms are expressed in aortic endothelial cells. Isoform A is also expressed in liver; isoform B in smooth muscle cells and fibroblasts; isoform C in aortic endothelial cells, smooth muscle cells, fibroblasts, liver and lung, and isoform D in smoot
Database Links

STRING: 10116.ENSRNOP00000062928

UniGene: Rn.7000

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