All
  • All
  • ELISA Kit
  • Protein
  • Antibody
  • Molecular Biology Product
  • Small Molecule
  • Peptide
All
  • All
  • ELISA Kit
  • Protein
  • Antibody
  • Molecular Biology Product
  • Small Molecule
  • Peptide

BTN1A1 (Nelmastobart Biosimilar) Recombinant Monoclonal Antibody

Datasheet
Code CSB-RA615684MB1HU
Size US$9799
Order now
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Uniprot No.
Q13410
Target Names
BTN1A1
Alternative Names
Anti-butyrophilin 1A1 mAb(STCube/MD Anderson Cancer Center) research-grade biosimilar; Anti STT-003 Ab research-grade biosimilar; HSTC810 research-grade biosimilar; HSTC 810 research-grade biosimilar; STT 003 research-grade biosimilar ;BTN1A1 antibody; BTN antibody; Butyrophilin subfamily 1 member A1 antibody; BT antibody
Species Reactivity
Human
Immunogen
Recombinant Human BTN1A1 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
0.01M PBS，pH7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Notes
Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity > 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.
Lead Time
3-4 weeks
Description

This recombinant monoclonal antibody is developed as a research-grade biosimilar to Nelmastobart, targeting BTN1A1 (butyrophilin subfamily 1 member A1), a transmembrane glycoprotein belonging to the immunoglobulin superfamily. BTN1A1 is expressed on epithelial cells and antigen-presenting cells, where it plays a regulatory role in immune responses and T cell modulation. This protein is involved in lipid metabolism regulation and has been implicated in various pathological conditions, including inflammatory disorders and cancer. BTN1A1 expression patterns have been associated with tumor progression and immune evasion mechanisms in multiple malignancies, making it an important target for immunological research.

Nelmastobart represents an investigational therapeutic antibody designed to modulate BTN1A1-mediated immune regulation. This biosimilar antibody provides researchers with a valuable tool for investigating BTN1A1 biology, exploring its role in immune checkpoint pathways, and studying potential therapeutic interventions in oncology and immunology. The antibody enables detailed examination of BTN1A1 function in cellular signaling, immune cell interactions, and disease-associated mechanisms.

Usage
It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

Related Products

BTN1A1 Antibodies

BTN1A1 Proteins

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Gene References into Functions
  1. Data illustrated the importance of Akt1 in mammary epithelial cell proliferation, as well as in the regulation of Btn1a1 and subsequent expression of ss-casein. PMID: 21915327
  2. PRY/SPRY/B30.2 domain of butyrophilin 1A1 (BTN1A1) binds to xanthine oxidoreductase PMID: 19531472
Subcellular Location
Membrane; Single-pass type I membrane protein. Secreted.
Protein Families
Immunoglobulin superfamily, BTN/MOG family
Database Links

HGNC: 1135

OMIM: 601610

KEGG: hsa:696

STRING: 9606.ENSP00000244513

UniGene: Hs.153058

Promotions
Reward For Reviews
Free antibody trial
Contact Us

  Email: [email protected]
  Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of email
Email
[email protected]
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2026 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Privacy Policy
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*