ABI3BP Antibody

Code CSB-PA772035LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA772035LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA772035LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ABI3BP Polyclonal antibody
Uniprot No.
Target Names
ABI3BP
Alternative Names
ABI gene family member 3 (NESH) binding protein antibody; ABI gene family member 3 binding protein antibody; ABI gene family member 3-binding protein antibody; ABI3BP antibody; FLJ41743 antibody; FLJ41754 antibody; Nesh binding protein antibody; Nesh BP antibody; Nesh-binding protein antibody; NeshBP antibody; Target of Nesh SH3 antibody; Target of Nesh-SH3 antibody; Tarsh antibody; TARSH_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Target of Nesh-SH3 protein (601-900AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ABI3BP Antibody (Product code: CSB-PA772035LA01HU) is Non-conjugated. For ABI3BP Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA772035LB01HU ABI3BP Antibody, HRP conjugated ELISA
FITC CSB-PA772035LC01HU ABI3BP Antibody, FITC conjugated
Biotin CSB-PA772035LD01HU ABI3BP Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. ABI3BP is a susceptibility gene for Kashin-Beck disease in the Chinese Han population. PMID: 24442417
  2. Thus, TARSH presumably represents a trigger gene for evoking cellular senescence, which has also been suggested to be involved in the prevention of tumorigenesis. PMID: 15752759
  3. expression of TARSH mRNA is remarkably downregulated in all lung cancer cell lines examined; also TARSH expression was significantly low in all of the tumor specimens when compared to the expression in corresponding non-neoplastic lung tissue specimens PMID: 16205947
  4. The loss of ABI3BP expression could play a functional role in thyroid tumorigenesis. PMID: 18559958
  5. These results suggest that TARSH plays an important role in proliferation of replicative senescence and may serve as a trigger of tumor development. PMID: 19338757

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Involvement in disease
Defects in ABI3BP has been found in a patient with isolated coloboma, a defect of the eye characterized by the absence of ocular structures due to abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Isolated colobomas may be associated with an abnormally small eye (microphthalmia) or small cornea.
Subcellular Location
Secreted.
Tissue Specificity
Expressed in brain, heart, lung, liver, pancreas kidney and placenta.
Database Links

HGNC: 17265

OMIM: 606279

KEGG: hsa:25890

STRING: 9606.ENSP00000284322

UniGene: Hs.477015

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