AMPD3 Antibody

Code CSB-PA008865
Size US$119
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Product Details

Uniprot No.
Target Names
AMPD3
Alternative Names
Adenosine monophosphate deaminase (isoform E) antibody; Adenosine monophosphate deaminase 3 antibody; AMP aminohydrolase antibody; AMP deaminase 3 antibody; AMP deaminase isoform E antibody; Ampd3 antibody; AMPD3_HUMAN antibody; Erythrocyte AMP deaminase antibody; Erythrocyte specific AMP deaminase antibody; Erythrocyte specific protein antibody; Erythrocyte type AMP deaminase antibody; Erythroid Marker antibody; Myoadenylate deaminase antibody; OTTHUMP00000230743 antibody; OTTHUMP00000230746 antibody; OTTHUMP00000230747 antibody; OTTHUMP00000230748 antibody; OTTHUMP00000230749 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human AMPD3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
AMP deaminase plays a critical role in energy metabolism.
Gene References into Functions
  1. N-terminal sequence and distal histidine residues are responsible for pH-regulated cytoplasmic membrane binding PMID: 12213808
  2. mtDNA deletion coordinately induces AMP deaminase to contribute to the loss of atrial adenine nucleotides through degrading AMP excessively. PMID: 12604357
  3. The primary underlying mechanism for increased catabolic flow through the AMP deaminase reaction in circulating erythrocytes of individuals with familial phosphofructokinase deficiency is Ca2+-calmodulin activation of AMP deaminase isoform E. PMID: 16670071
Involvement in disease
Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE)
Protein Families
Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family
Database Links

HGNC: 470

OMIM: 102772

KEGG: hsa:272

STRING: 9606.ENSP00000379802

UniGene: Hs.501890

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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