ANXA2R Antibody

Datasheet

Code	CSB-PA827389
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA827389(ANXA2R Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA827389(ANXA2R Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q3ZCQ2

Target Names

ANXA2R

Alternative Names

Annexin 2 receptor antibody; Annexin II receptor antibody; Annexin-2 receptor antibody; ANXA2R antibody; AX2R antibody; AX2R_HUMAN antibody; AXIIR antibody; C5orf39 antibody; Chromosome 5 open reading frame 39 antibody; LOC389289 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human ANXA2R

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.

Gene References into Functions

Overexpression of AX2R significantly inhibited cell proliferation, migration and tube formation in both types of endothelial cells and increased the expression of KLF2, mediating VEGF and VEGFR2. PMID: 29694949
Data highlighted the crucial role of AXIIR in reducing Mum2C cell viability through inducing apoptosis, while autophagy played a protective role in this process. PMID: 27183438
these subsequent effects might be via suppressing the expression of matrix metalloproteinase 2 and matrix metalloproteinase 9. ... AXIIR participates in angiogenesis, and may be a potential therapeutic target for angiogenesis related diseases PMID: 25633185
AXIIR acts as a novel inducer of apoptosis in human cells, partially through activating Caspase-8. PMID: 23640736
Results show that AXII and AXIIR play important roles in multiple myeloma (MM) and that targeting the AXII/AXIIR axis may be a novel therapeutic approach for MM. PMID: 22223826
analysis of the annexin II receptor on human marrow stromal cells PMID: 16895901
annexin II and its receptor axis play a central role in prostate cancer metastasis, and prostate cancer utilizes the hematopoietic stem cell homing mechanisms to gain access to the niche. PMID: 18636554

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Tissue Specificity

Widely expressed. Highly expressed in lymphocytes. Expressed in both resting CD4(+) and CD8(+) T-cells.

Database Links

HGNC: 33463

OMIM: 611296

KEGG: hsa:389289

STRING: 9606.ENSP00000315915

UniGene: Hs.529385

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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