B3GNT5 Antibody

Datasheet

Code	CSB-PA002503EA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA002503EA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA002503EA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) B3GNT5 Polyclonal antibody

Uniprot No.

Q9BYG0

Target Names

B3GNT5

Alternative Names

B3GNT5Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase antibody; EC 2.4.1.206 antibody; Lactotriaosylceramide synthase antibody; Lc(3)Cer synthase antibody; Lc3 synthase antibody; UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5 antibody; BGnT-5 antibody; Beta-1,3-Gn-T5 antibody; Beta-1,3-N-acetylglucosaminyltransferase 5 antibody; Beta3Gn-T5 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase protein (65-344AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The B3GNT5 Antibody (Product code: CSB-PA002503EA01HU) is Non-conjugated. For B3GNT5 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA002503EB01HU	B3GNT5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA002503EC01HU	B3GNT5 Antibody, FITC conjugated
Biotin	CSB-PA002503ED01HU	B3GNT5 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

Gene References into Functions

bone marrow samples of acute myeloid leukemia patients had 16-fold higher expression of B3GNT5 than those of healthy donors PMID: 22411838
Helicobacter pylori induces beta3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x PMID: 18483624

Subcellular Location

Golgi apparatus membrane; Single-pass type II membrane protein.

Protein Families

Glycosyltransferase 31 family

Tissue Specificity

Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus.

Database Links

HGNC: 15684

OMIM: 615333

KEGG: hsa:84002

STRING: 9606.ENSP00000316173

UniGene: Hs.718506

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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