B3GNT5 Antibody

Code CSB-PA002503EA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA002503EA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA002503EA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) B3GNT5 Polyclonal antibody
Uniprot No.
Target Names
B3GNT5
Alternative Names
B3GNT5Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase antibody; EC 2.4.1.206 antibody; Lactotriaosylceramide synthase antibody; Lc(3)Cer synthase antibody; Lc3 synthase antibody; UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5 antibody; BGnT-5 antibody; Beta-1,3-Gn-T5 antibody; Beta-1,3-N-acetylglucosaminyltransferase 5 antibody; Beta3Gn-T5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase protein (65-344AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The B3GNT5 Antibody (Product code: CSB-PA002503EA01HU) is Non-conjugated. For B3GNT5 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA002503EB01HU B3GNT5 Antibody, HRP conjugated ELISA
FITC CSB-PA002503EC01HU B3GNT5 Antibody, FITC conjugated
Biotin CSB-PA002503ED01HU B3GNT5 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.
Gene References into Functions
  1. bone marrow samples of acute myeloid leukemia patients had 16-fold higher expression of B3GNT5 than those of healthy donors PMID: 22411838
  2. Helicobacter pylori induces beta3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x PMID: 18483624
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 31 family
Tissue Specificity
Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus.
Database Links

HGNC: 15684

OMIM: 615333

KEGG: hsa:84002

STRING: 9606.ENSP00000316173

UniGene: Hs.718506

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