CCNL2 Antibody

Code CSB-PA004830GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CCNL2
Alternative Names
CCNL2 antibody; SB138Cyclin-L2 antibody; Paneth cell-enhanced expression protein antibody
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CCNL2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.
Gene References into Functions
  1. Therefore, cyclin L2-mediated control of SAMHD1 levels in macrophages supports HIV-1 replication. PMID: 25532805
  2. CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome. PMID: 24218572
  3. characterize cyclin L2 as a highly mobile component of nuclear speckles and suggest that DYRK1A may regulate splicing by phosphorylation of cyclin L2 PMID: 14623875
  4. represents a new member of the cyclin family, which might regulate the transcription and RNA processing of certain apoptosis-related factors PMID: 14684736
Subcellular Location
Nucleus speckle. Nucleus, nucleoplasm.
Protein Families
Cyclin family, Cyclin L subfamily
Tissue Specificity
Widely expressed.
Database Links

HGNC: 20570

OMIM: 613482

KEGG: hsa:81669

STRING: 9606.ENSP00000383611

UniGene: Hs.515704

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