CLCA4 Antibody

Code CSB-PA584850
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA584850(CLCA4 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
CLCA4
Alternative Names
30 kDa form antibody; CaCC-2 antibody; Calcium-activated chloride channel family member 4 antibody; Calcium-activated chloride channel protein 2 antibody; Calcium-activated chloride channel regulator 4 antibody; Clca4 antibody; CLCA4_HUMAN antibody; hCaCC-2 antibody; hCLCA4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human CLCA4
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:10-1:50
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in mediating calcium-activated chloride conductance.
Gene References into Functions
  1. CLCA4 and CLCA2 play complementary but distinct roles in epithelial differentiation PMID: 24386311
  2. CLCA4 modulates the capability to express residual chloride secretion in colonic tissue. PMID: 23073314
  3. CLCA1 and CLCA4 may have roles as modulators of the gastrointestinal basic defect in cystic fibrosis PMID: 15490240
Subcellular Location
Cell membrane; Single-pass membrane protein. Apical cell membrane. Secreted.
Protein Families
CLCR family
Tissue Specificity
Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa.
Database Links

HGNC: 2018

OMIM: 616857

KEGG: hsa:22802

STRING: 9606.ENSP00000359594

UniGene: Hs.567422

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