COG7 Antibody

Datasheet

Code	CSB-PA005711ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA005711ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA005711ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) COG7 Polyclonal antibody

Uniprot No.

P83436

Target Names

COG7

Alternative Names

CDG2E antibody; COG complex subunit 7 antibody; cog7 antibody; COG7_HUMAN antibody; Component of oligomeric Golgi complex 7 antibody; Conserved oligomeric Golgi complex component 7 antibody; Conserved oligomeric Golgi complex subunit 7 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Conserved oligomeric Golgi complex subunit 7 protein (511-770AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Required for normal Golgi function.

Gene References into Functions

Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex. PMID: 25331899
COG5- and COG7 subunits play distinctive roles in controlling Golgi structure and function PMID: 16051600
Retrograde transport of multiple Golgi proteins to the ER in COG-7-deficient patient fibroblasts via brefeldin A-induced tubules was significantly slower than occurs in normal fibroblasts. PMID: 16510524
A homozygous, intronic splice site mutation (c.169+4A>C) of the COG7 gene was identified in 3 patients with Congenital Disorder of Glycosylation type IIe. PMID: 17356545
A new mutation in COG7 extends the spectrum of COG subunit deficiencies. PMID: 19577670

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Involvement in disease

Congenital disorder of glycosylation 2E (CDG2E)

Subcellular Location

Golgi apparatus membrane; Peripheral membrane protein.

Protein Families

COG7 family

Database Links

HGNC: 18622

OMIM: 606978

KEGG: hsa:91949

STRING: 9606.ENSP00000305442

UniGene: Hs.185807

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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