COX19 Antibody

Code CSB-PA586799
Size US$166
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Image
  • The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA586799(COX19 Antibody) at dilution 1/50. (Original magnification: ×200)
  • The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA586799(COX19 Antibody) at dilution 1/50. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
COX19
Alternative Names
COX19Cytochrome c oxidase assembly protein COX19 antibody; hCOX19 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human COX19
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:10000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for the transduction of an SCO1-dependent redox signal from the mitochondrion to ATP7A to regulate cellular copper homeostasis. May be required for the assembly of mitochondrial cytochrome c oxidase.
Gene References into Functions
  1. COX19 is necessary for the transduction of a SCO1-dependent mitochondrial redox signal that regulates ATP7A-mediated cellular copper efflux. PMID: 23345593
  2. Both hCox18p and hCox19p present significant amino acid identity with the corresponding yeast polypeptides and reveal highly conserved functional domains. PMID: 16212937
Subcellular Location
Cytoplasm, cytosol. Mitochondrion intermembrane space. Mitochondrion.
Protein Families
COX19 family
Tissue Specificity
Ubiquitously expressed. Highly expressed in skeletal muscle.
Database Links

HGNC: 28074

OMIM: 610429

KEGG: hsa:90639

STRING: 9606.ENSP00000342015

UniGene: Hs.121593

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