Capsid protein VP1 Antibody

^{Rare Species}

Datasheet

Code	CSB-PA362102LA01HPM
Size	US$166
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Human parvovirus B19 N/A Polyclonal antibody

Uniprot No.

P07299

Target Names

N/A

Alternative Names

Minor capsid protein VP1 antibody; EC 3.1.1.4 antibody; Coat protein VP1 antibody

Raised in

Rabbit

Species Reactivity

Human parvovirus B19

Immunogen

Recombinant Human parvovirus B19 Capsid protein VP1 protein (228-781AA)

Immunogen Species

Human parvovirus B19

Conjugate

Non-conjugated

The Capsid protein VP1 Antibody (Product code: CSB-PA362102LA01HPM) is Non-conjugated. For Capsid protein VP1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA362102LB01HPM	Capsid protein VP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA362102LC01HPM	Capsid protein VP1 Antibody, FITC conjugated
Biotin	CSB-PA362102LD01HPM	Capsid protein VP1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 20 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Binds to erythroid progenitor cells expressing high levels of P antigen and uses host ITGA5-ITGB1 and XRCC5/Ku80 autoantigen as coreceptors on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.

Subcellular Location

[Isoform Minor capsid protein VP1]: Virion. Host nucleus. Host cytoplasm.; [Isoform Major capsid protein VP2]: Virion. Host nucleus. Host cytoplasm.

Protein Families

Parvoviridae capsid protein family

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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