Cd207 Antibody

1. Binding analysis between purified long and short forms of langerin and a series of keratin sulfate disaccharide components shows that the binding critically requires the 6-sulfation of Gal and that the long form of langerin displays higher affinity than the short form. PMID: 29631057
2. Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent PMID: 27903635
3. Data show that Candida albicans and Candida tropicalis preferentially localized in (and persisted within) a sub- population of Peyer's patch Langerin-positive dendritic cells. PMID: 26386376
4. Langerin is expressed by the XCR1(+) "DC1" population of mice. PMID: 25516751
5. Langerin+ dermal dendritic cells appear to be site- and strain-specific PMID: 24629018
6. model of epicutaneous ovalbumin sensitization inducing an inflammatory skin resembling atopic dermatitis (AD) to explore the role of CD207 in the pathogenesis of AD PMID: 23117802
7. Langerin-positive dendritic cells appear to be the predominant, though not exclusive, population responsible for in vivo transport of anti-DEC-205 antibodies from the skin to the draining lymph nodes in steady state and inflammation. PMID: 22291181
8. Data demonstrated that CD207(+) CD8alpha(+) thymic DCs do not share a common origin with T cells but originate from intrathymic precursors. PMID: 21630253
9. The normal corneal epithelium is endowed with CD11c(+) Langerin+ cells that are LCs, whereas the stroma is endowed with a separate population of (non-LC) Langerin+ DCs. PMID: 21482644
10. Langerhan cells and (Langerin(+)) dermal dendritic cells thus seem to have a redundant function in regulating contact hypersensitivity PMID: 20703247
11. molecular cloning and expression of Langerin transcripts in dendritic cells PMID: 11978773
12. Developmentally regulated expression of Langerin isoforms provides a mechanism by which Langerin involvement in antigen uptake and processing could be regulated. PMID: 15191546
13. CD207 has a role in maintaining Birbeck granules but not in Langerhans cell function PMID: 15601833
14. Langerin may have an unanticipated role in cell-matrix interactions that modulate LC development, localization, or function PMID: 16557233
15. CD207 antigens manifest a high degree of colocalization around the nucleus of the Langerhans cells. PMID: 16941665
16. langerin(+) DCs patrol the dermis in the steady state and migrate to the skin DLNs charged with skin antigens PMID: 18086862
17. dermal Langerin(+) dendritic cells (DCs) are radiosensitive and display a distinct cell surface phenotype PMID: 18086865
18. Depletion of langerin(+) cells impaired intestinal IgA Ab responses after Topical transcutaneous immunization PMID: 18354155
19. Langerin(+) cells do promote T cell responses to skin Ags PMID: 18354196
20. In a knockin-mouse model of the immune response against Leishmania major parasites, langerin-expressing dendritic cells are, in general, dispensable for an efficient adaptive immune response against L. major parasites. PMID: 19124720
21. Despite a marginal zone location, CD207(+) DCs lacked identifying molecules for 3 different types of macrophages, localized in proximity and, in contrast to macrophages, marginal zone DCs were poor scavengers of soluble and particulate substrates PMID: 19168629
22. Langerhans cells(LC) and langerin(+) dermal dendritic cells(DC) represent distinct DC subsets that have specialized functions and that LC are important immunoregulatory cells PMID: 19218433

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KEGG: mmu:246278

STRING: 10090.ENSMUSP00000040746

UniGene: Mm.136079