DAZ4 Antibody

Code CSB-PA821404
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA821404(DAZ4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA821404(DAZ4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
DAZ4
Alternative Names
DAZ4Deleted in azoospermia protein 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human DAZ4
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:500-1:5000
IHC 1:5-1:20
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
Gene References into Functions
  1. Oligospermia seems to be promoted by removing DAZ4 copy. Deletion of DAZ2 and DAZ4 gene copies is associated with male infertility. PMID: 24878370
Involvement in disease
Spermatogenic failure Y-linked 2 (SPGFY2)
Subcellular Location
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
Protein Families
RRM DAZ family
Tissue Specificity
Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level).
Database Links

HGNC: 15966

OMIM: 400003

KEGG: hsa:57135

STRING: 9606.ENSP00000401363

UniGene: Hs.522868

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