ESD Antibody

Datasheet

Code	CSB-PA007823LA01HU
Size	US$166
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Image	Immunofluorescent analysis of U251 cells using CSB-PA007823LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ESD Polyclonal antibody

Uniprot No.

P10768

Target Names

ESD

Alternative Names

EC 3.1.2.12 antibody; Es-10 antibody; Es10 antibody; ESD antibody; ESTD_HUMAN antibody; Esterase 10 antibody; Esterase D antibody; Esterase D formylglutathione hydrolase antibody; FGH antibody; FGH, included antibody; FLJ11763 antibody; Methylumbelliferyl acetate deacetylase antibody; MGC139609 antibody; OTTHUMP00000018374 antibody; OTTHUMP00000040929 antibody; S formylglutathione hydrolase antibody; S-formylglutathione hydrolase antibody; S-formylglutathione hydrolase, included antibody; Sid 478 antibody; sid478 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human S-formylglutathione hydrolase protein (2-282AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ESD Antibody (Product code: CSB-PA007823LA01HU) is Non-conjugated. For ESD Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA007823LB01HU	ESD Antibody, HRP conjugated	ELISA
FITC	CSB-PA007823LC01HU	ESD Antibody, FITC conjugated
Biotin	CSB-PA007823LD01HU	ESD Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Serine hydrolase involved in the detoxification of formaldehyde.

Gene References into Functions

rs7996797 located on chr13q14.1-q14.2 near the ESD gene was the most significantly associated with hallux valgus in females in genome-wide association meta-analyses. PMID: 26337638
Abhydrolase domain-containing protein 11 and Esterase D predict the development of distant metastases and the presence of aggressive lung adenocarcinomas. PMID: 21596165
The analysis involved the data on nine polymorphic codominant loci: HP, GC, TF, PI, PGM1, GLO1, C3, ACP1, and ESD. The loci were selected by significance of differences in genotype frequencies between tuberculosis patients and healthy controls PMID: 12942785
Autoantibodies to EsteD and BB-CK produced in experimental autoimmune uveoretinitis -induced mice were also detected in some endogenous uveitis patients, suggesting that these proteins might be autoantigens. PMID: 18552983
catalytic triad residues--Ser-153, His264, and Asp230--involved in catalysis. Mutagenesis of any of the catalytic triad residues to alanine abolished the enzyme activity. Backbone amides of Leu54 & Met150 are involved in the formation of the oxyanion hole PMID: 19126594

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Subcellular Location

Cytoplasm. Cytoplasmic vesicle.

Protein Families

Esterase D family

Database Links

HGNC: 3465

OMIM: 133280

KEGG: hsa:2098

STRING: 9606.ENSP00000367992

UniGene: Hs.432491

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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