FANK1 Antibody

Datasheet

Code	CSB-PA819458HA01HU
Size	US$166
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Image	Immunofluorescence staining of MCF-7 cells with CSB-PA819458HA01HU at 1:333, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA819458HA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) FANK1 Polyclonal antibody

Uniprot No.

Q8TC84

Target Names

FANK1

Alternative Names

1700007B22Rik antibody; AI850911 antibody; Fank1 antibody; FANK1_HUMAN antibody; Fibronectin type 3 and ankyrin repeat domains 1 antibody; Fibronectin type 3 and ankyrin repeat domains protein 1 antibody; Fibronectin type III and ankyrin repeat domains 1 antibody; HSD13 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Fibronectin type 3 and ankyrin repeat domains protein 1 protein (1-345AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The FANK1 Antibody (Product code: CSB-PA819458HA01HU) is Non-conjugated. For FANK1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA819458HB01HU	FANK1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA819458HC01HU	FANK1 Antibody, FITC conjugated
Biotin	CSB-PA819458HD01HU	FANK1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis.

Gene References into Functions

RYBP activates FANK1-mediated activator protein 1 (AP-1) signaling pathway which contributes to tumor cell apoptosis. PMID: 27060496
we find evidence for many novel candidates, the strongest of which is FANK1, an imprinted gene that suppresses apoptosis, is expressed during meiosis in males. PMID: 25144706
the TNfnIII 1-5 repeats play an important role in PCO pathology. PMID: 25515583
found that Jab1 (Jun activation domain-binding protein 1), a co-activator of AP-1, specifically interacted with Fank1 PMID: 20978819
FANK1 may have a role in regulating gene expression in the transition from the meiotic phase to the haploid phase during spermatogenesis PMID: 17604233

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Subcellular Location

Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium.

Tissue Specificity

Mostly restricted to testis.

Database Links

HGNC: 23527

OMIM: 611640

KEGG: hsa:92565

STRING: 9606.ENSP00000357682

UniGene: Hs.352591

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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