FBXO9 Antibody

Datasheet

Code	CSB-PA891719LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA891719LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA891719LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) FBXO9 Polyclonal antibody

Uniprot No.

Q9UK97

Target Names

FBXO9

Alternative Names

Cross-immune reaction antigen 1 antibody; dJ341E18.2 antibody; DKFZp434C0118 antibody; F-box only protein 9 antibody; Fbp24 antibody; FBX09 antibody; FBX9 antibody; FBX9_HUMAN antibody; Fbxo9 antibody; KIAA0936 antibody; NY REN 57 antibody; OTTHUMP00000016628 antibody; OTTHUMP00000016629 antibody; OTTHUMP00000214588 antibody; Renal carcinoma antigen NY-REN-57 antibody; VCIA1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human F-box only protein 9 protein (13-111AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The FBXO9 Antibody (Product code: CSB-PA891719LA01HU) is Non-conjugated. For FBXO9 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA891719LB01HU	FBXO9 Antibody, HRP conjugated	ELISA
FITC	CSB-PA891719LC01HU	FBXO9 Antibody, FITC conjugated
Biotin	CSB-PA891719LD01HU	FBXO9 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.

Subcellular Location

Cytoplasm.

Database Links

HGNC: 13588

OMIM: 609091

KEGG: hsa:26268

STRING: 9606.ENSP00000244426

UniGene: Hs.216653

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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