GLYAT Antibody

Datasheet

Code	CSB-PA009558GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q6IB77

Target Names

GLYAT

Alternative Names

GLYAT antibody; ACGNAT antibody; CAT antibody; GATGlycine N-acyltransferase antibody; EC 2.3.1.13 antibody; Acyl-CoA:glycine N-acyltransferase antibody; AAc antibody; Aralkyl acyl-CoA N-acyltransferase antibody; Aralkyl acyl-CoA:amino acid N-acyltransferase antibody; Benzoyl-coenzyme A:glycine N-acyltransferase antibody; Glycine N-benzoyltransferase antibody; EC 2.3.1.71 antibody; HRP-1(CLP) antibody

Species Reactivity

Human,Mouse,Rat

Immunogen

Human GLYAT

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.

Gene References into Functions

GLYAT exhibits mechanistic kinetic cooperativity towards its substrate glycine. PMID: 28759163
Data indicate that Afrikaner caucasians have a Q61L single nucleotide polymorphism (SNP) occurring at a high frequency (12%). PMID: 26149650
SNP variations causing amino acid substitutions in the human GLYAT gene influence the kinetic properties of the enzyme. PMID: 23237781
We identify GLYAT gene which appears to co-regulate bone size phenotypes (BSPs) and appendicular lean mass (ALM). PMID: 23108985
hGLYAT is a good candidate as a novel marker of hepatocellular carcinoma and may be a key molecule in the transition between differentiation and carcinogenesis of liver cells. PMID: 22475485
The aim of this work was to report a comprehensive investigation of GLYAT genetic polymorphisms in DNA samples from 55 subjects of French Caucasian origin. PMID: 20925583

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Subcellular Location

Mitochondrion.

Protein Families

Glycine N-acyltransferase family

Tissue Specificity

Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers.

Database Links

HGNC: 13734

OMIM: 607424

KEGG: hsa:10249

STRING: 9606.ENSP00000340200

UniGene: Hs.145384

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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