GNL2 Antibody

Code CSB-PA618806LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GNL2 Polyclonal antibody
Uniprot No.
Target Names
GNL2
Alternative Names
Autoantigen NGP-1 antibody; Autoantigen NGP1 antibody; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein antibody; FLJ40906 antibody; GNL2 antibody; Guanine nucleotide binding protein-like 2 (nucleolar) antibody; HUMAUANTIG antibody; NGP1 antibody; NOG2_HUMAN antibody; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen antibody; nucleolar G-protein gene 1 antibody; Nucleolar GTP binding protein 2 antibody; Nucleolar GTP-binding protein 2 antibody; Nucleolar GTPase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nucleolar GTP-binding protein 2 protein (1-731AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The GNL2 Antibody (Product code: CSB-PA618806LA01HU) is Non-conjugated. For GNL2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA618806LB01HU GNL2 Antibody, HRP conjugated ELISA
FITC CSB-PA618806LC01HU GNL2 Antibody, FITC conjugated
Biotin CSB-PA618806LD01HU GNL2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
Gene References into Functions
  1. NGP-1 promotes cell cycle progression through the activation of the p53/p21(Cip-1/Waf1) pathway. PMID: 26203195
  2. GNL2 and SEC13 are required for nonsense-mediated mRNA decay pathway in human cells. PMID: 25452588
Subcellular Location
Nucleus, nucleolus.
Protein Families
TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily
Tissue Specificity
Widely expressed, with the highest expression level in testis.
Database Links

HGNC: 29925

OMIM: 609365

KEGG: hsa:29889

STRING: 9606.ENSP00000362153

UniGene: Hs.75528

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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