HFM1 Antibody

Code CSB-PA010325LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA010325LA01HU at dilution of 1:100
  • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA010325LA01HU at dilution of 1:100
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HFM1 Polyclonal antibody
Uniprot No.
Target Names
HFM1
Alternative Names
HFM1 antibody; SEC3D1Probable ATP-dependent DNA helicase HFM1 antibody; EC 3.6.4.12 antibody; SEC63 domain-containing protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable ATP-dependent DNA helicase HFM1 protein (121-420AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The HFM1 Antibody (Product code: CSB-PA010325LA01HU) is Non-conjugated. For HFM1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010325LB01HU HFM1 Antibody, HRP conjugated ELISA
FITC CSB-PA010325LC01HU HFM1 Antibody, FITC conjugated
Biotin CSB-PA010325LD01HU HFM1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for crossover formation and complete synapsis of homologous chromosomes during meiosis.
Gene References into Functions
  1. Data suggest that HFM1 gene might be associated with primary ovarian insufficiency in Chinese population. PMID: 26679638
  2. Exome sequencing of two Chinese sisters with primary ovarian insufficiency and their parents identified a shared compound heterozygous mutation in a meiotic gene, HFM1, which encodes a protein necessary for homologous recombination of chromosomes. PMID: 24597873
  3. hHFM1 is the evolutionally conserved putative human DNA helicase, which may function as a modulator for genome integrity in germ-line tissues. PMID: 17286053
Involvement in disease
Premature ovarian failure 9 (POF9)
Protein Families
Helicase family, SKI2 subfamily
Tissue Specificity
Preferentially expressed in testis and ovary.
Database Links

HGNC: 20193

OMIM: 615684

KEGG: hsa:164045

STRING: 9606.ENSP00000359454

UniGene: Hs.454818

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