HOXD8 Antibody

Code CSB-PA009250
Size US$119
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Product Details

Uniprot No.
Target Names
HOXD8
Alternative Names
homeo box 4E antibody; homeo box D8 antibody; Homeobox 4E antibody; homeobox D8 antibody; homeobox protein 5.4 antibody; Homeobox protein Hox-4E antibody; Homeobox protein Hox-5.4 antibody; Homeobox protein Hox-D8 antibody; Hox-4.5 antibody; Hox-4.5, mouse, homolog of antibody; Hox-4E antibody; Hox-5.4 antibody; HOX4 antibody; HOX4E antibody; Hoxd8 antibody; HXD8_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human HoxD8.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Gene References into Functions
  1. HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer PMID: 28457970
  2. microRNA-520a-3p inhibits proliferation and cancer stem cell phenotype by targeting HOXD8 in non small cell lung cancer cells and restoration of microRNA-520a-3p might be a therapeutic strategy to reverse gefitinib resistance. PMID: 27748920
  3. Prox1 and HoxD8 play important roles in the maturation and maintenance of lymphatic vessels. PMID: 19825936
Subcellular Location
Nucleus.
Protein Families
Antp homeobox family
Database Links

HGNC: 5139

OMIM: 142985

KEGG: hsa:3234

STRING: 9606.ENSP00000315949

UniGene: Hs.301963

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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