ICAM5 Antibody

Code CSB-PA468797
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA468797(ICAM5 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA468797(ICAM5 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
ICAM5
Alternative Names
ICAM5 antibody; TLCN antibody; TLNIntercellular adhesion molecule 5 antibody; ICAM-5 antibody; Telencephalin antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human ICAM5
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
Gene References into Functions
  1. Here the authors identify neuron-specific intercellular adhesion molecule 5 (ICAM-5/telencephalin) as a cellular receptor for sialic acid-dependent and -independent entry of enterovirus D68. PMID: 27923705
  2. ICAM5 V301I and rs281439 variants may contribute to the susceptibility of breast cancer. [Meta-analysis] PMID: 23079714
  3. A specific microenvironment facilitating ARF6-mediated mobilization of TLN that contributes to promotion of dendritic spine development. PMID: 22781129
  4. study does not confirm association between ICAM 5 V3001 polymorphism and breast cancer risk PMID: 16434609
  5. ICAM-5 is involved in immune privilege of the brain and acts as an anti-inflammatory agent. PMID: 18223167

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Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Families
Immunoglobulin superfamily, ICAM family
Tissue Specificity
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
Database Links

HGNC: 5348

OMIM: 601852

KEGG: hsa:7087

STRING: 9606.ENSP00000221980

UniGene: Hs.465862

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