KCNH6 Antibody

Code CSB-PA678002
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA678002(KCNH6 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA678002(KCNH6 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
KCNH6
Alternative Names
KCNH6 antibody; ERG2 antibody; Potassium voltage-gated channel subfamily H member 6 antibody; Ether-a-go-go-related gene potassium channel 2 antibody; ERG-2 antibody; Eag-related protein 2 antibody; Ether-a-go-go-related protein 2 antibody; hERG-2 antibody; hERG2 antibody; Voltage-gated potassium channel subunit Kv11.2 antibody
Raised in
Rabbit
Species Reactivity
Human,Rat
Immunogen
Fusion protein of Human KCNH6
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current. Channel properties may be modulated by cAMP and subunit assembly.
Gene References into Functions
  1. results indicated that downregulation of miR-224 suppressed cell growth and resulted in the enhancement of cell apoptosis through activation of the ERG2-BAK-induced apoptosis pathway PMID: 25783051
  2. Transcripts for HERG1 were present in all adenomas and although transcripts for HERG2 and HERG3 were also detected, their expression level was more variable. PMID: 12634931
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.2/KCNH6 sub-subfamily
Tissue Specificity
Expressed in prolactin-secreting adenomas.
Database Links

HGNC: 18862

OMIM: 608168

KEGG: hsa:81033

STRING: 9606.ENSP00000463533

UniGene: Hs.591177

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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