LCOR Antibody, Biotin conjugated

1. Taken together, these results provide new insights into the mechanism of action of LCoR and RIP140 and highlight their strong interplay for the control of gene expression and cell proliferation in breast cancer cells. PMID: 28414308
2. miR-199a promotes stem cell properties in mammary stem cells and breast cancer stem cells by directly repressing nuclear receptor corepressor LCOR, which primes interferon responses. PMID: 28530657
3. LCoR recruitment by KLF6 regulates expression of the cyclin-dependent kinase inhibitor CDKN1A gene. PMID: 22277651
4. Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase. PMID: 21856747
5. These results showed that the presence of miR-615-3p repressed the expression of LCoR, a derepressor of peroxisome proliferator-activated receptor gamma (PPARgamma). PMID: 21565892
6. Data show that LCoR (ligand-dependent nuclear receptor corepressor) represents a class of corepressor that attenuates agonist-activated nuclear receptor signaling by multiple mechanisms [Ligand-dependent nuclear receptor corepressor]. PMID: 12535528
7. HDAC6 can function as a cofactor of LCoR but they can act to enhance expression of specific estrogen-regulated genes PMID: 19744931
8. role for LCoR and CtBP1 as attenuators of progesterone-regulated transcription, but LCoR and CtBP1 can act to enhance transcription of some genes PMID: 19744932

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HGNC: 29503

OMIM: 607698

KEGG: hsa:84458

STRING: 9606.ENSP00000348298

UniGene: Hs.427927