LYRM1 Antibody

Datasheet

Code	CSB-PA013272LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA013272LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LYRM1 Polyclonal antibody

Uniprot No.

O43325

Target Names

LYRM1

Alternative Names

1110065L10Rik antibody; 2310004B22Rik antibody; 4930404J24Rik antibody; A211C6.1 antibody; LYR motif containing 1 antibody; LYR motif containing protein 1 antibody; LYR motif-containing protein 1 antibody; LYRM 1 antibody; lyrm1 antibody; LYRM1_HUMAN antibody; OTTHUMP00000162292 antibody; OTTMUSP00000031126 antibody; OTTMUSP00000031127 antibody; OTTMUSP00000031128 antibody; OTTMUSP00000031129 antibody; RGD1563498 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human LYR motif-containing protein 1 protein (1-122AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The LYRM1 Antibody (Product code: CSB-PA013272LA01HU) is Non-conjugated. For LYRM1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA013272LB01HU	LYRM1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA013272LC01HU	LYRM1 Antibody, FITC conjugated
Biotin	CSB-PA013272LD01HU	LYRM1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May promote cell proliferation and inhibition of apoptosis of preadipocytes.

Gene References into Functions

alpha-LA protects 3T3-L1 adipocytes from LYRM1-induced insulin resistance partially via its capacity to restore mitochondrial function and/or increase phosphorylation of IRS-1 and Akt. PMID: 22820890
overexpression of LYRM1 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of LYRM1-induced insulin resistance PMID: 20826099
Data suggest that LYRM1 might have the potential to modulate cell growth, apoptosis, and heart development. PMID: 20938407
By increasing cell proliferation and lowering the rate of apoptosis, LYRM1 has the potential to modulate the size of the preadipocyte pool and influence adipose tissue homeostasis PMID: 19022914

Involvement in disease

When overexpressed, may be involved in obesity-associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes.

Subcellular Location

Nucleus.

Protein Families

Complex I LYR family

Tissue Specificity

High levels in adipose tissue.

Database Links

HGNC: 25074

OMIM: 614709

KEGG: hsa:57149

STRING: 9606.ENSP00000219168

UniGene: Hs.745012

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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