MAP7 Antibody

Datasheet

Code	CSB-PA013443GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q14244

Target Names

MAP7

Alternative Names

dJ325F22.2 (microtubule-associated protein 7 (EMAP115; E-MAP- 115)) antibody; E MAP 115 antibody; E-MAP-115 antibody; EMAP115 antibody; Ensconsin antibody; Epithelial microtubule associated protein of 115 kDa antibody; Epithelial microtubule-associated protein of 115 kDa antibody; MAP 7 antibody; MAP-7 antibody; Map7 antibody; MAP7_HUMAN antibody; Microtubule associated protein 7 antibody; Microtubule-associated protein 7 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human MAP7

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments.

Gene References into Functions

findings demonstrate the efficacy of quantitative proteomics for identifying effector-host protein interactions and suggest that vesicular trafficking is a crucial cellular process that may be targeted by NleB1 and EspL through their interaction with ensconsin. PMID: 27018634
Study of 117 patients suggests MAP7 as a candidate gene for sacral dysgenesis. However, we were unable to detect any sacral defects in the MAP7 knockout mice. PMID: 15218243
the expression ratio of Map7/B2M may serve as a valuable prognostic marker in patients with Stage II colon cancer PMID: 18695889

Subcellular Location

Cytoplasm, perinuclear region. Basolateral cell membrane. Cytoplasm, cytoskeleton. Note=Colocalized on microtubules. An intracellular redistribution is triggered during induction of keratinocyte terminal differentiation from microtubules with a perinuclear localization to cortical microtubules organized in spike-like bundles facing intercellular contacts.

Protein Families

MAP7 family

Tissue Specificity

Expressed in the skin and cells of epithelial origin. Predominantly expressed in the suprabasal layers of the normal epidermis and relatively abundant in squamous cell carcinomas but barely detectable in basal cell carcinomas.

Database Links

HGNC: 6869

OMIM: 604108

KEGG: hsa:9053

STRING: 9606.ENSP00000414712

UniGene: Hs.486548

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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