MED13 Antibody

Datasheet

Code	CSB-PA080113
Size	US$119
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9UHV7

Target Names

MED13

Alternative Names

MED13 antibody; ARC250 antibody; KIAA0593 antibody; THRAP1 antibody; TRAP240 antibody; Mediator of RNA polymerase II transcription subunit 13 antibody; Activator-recruited cofactor 250 kDa component antibody; ARC250 antibody; Mediator complex subunit 13 antibody; Thyroid hormone receptor-associated protein 1 antibody; Thyroid hormone receptor-associated protein complex 240 kDa component antibody; Trap240 antibody; Vitamin D3 receptor-interacting protein complex component DRIP250 antibody; DRIP250 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human TRAP240.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:40000

Protocols

Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene References into Functions

Each of HSPA4 and MED13 mutations were detected in GC. PMID: 27129500
Cardiac overexpression of MED13 in transgenic mice confers a lean phenotype that is associated with increased lipid uptake, beta-oxidation and mitochondrial content in white adipose tissue and liver PMID: 25422356
Med12 and Med13 are critical for human CDK8 subcomplex -dependent repression, whereas CDK8 kinase activity is not PMID: 19240132

Subcellular Location

Nucleus.

Protein Families

Mediator complex subunit 13 family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 22474

OMIM: 603808

KEGG: hsa:9969

STRING: 9606.ENSP00000380888

UniGene: Hs.282678

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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