MED22 Antibody

Code CSB-PA620882LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA620882LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA620882LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MED22 Polyclonal antibody
Uniprot No.
Target Names
MED22
Alternative Names
MED22 antibody; SURF5Mediator of RNA polymerase II transcription subunit 22 antibody; Mediator complex subunit 22 antibody; Surfeit locus protein 5 antibody; Surf-5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mediator of RNA polymerase II transcription subunit 22 protein (2-140AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MED22 Antibody (Product code: CSB-PA620882LA01HU) is Non-conjugated. For MED22 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA620882LB01HU MED22 Antibody, HRP conjugated ELISA
FITC CSB-PA620882LC01HU MED22 Antibody, FITC conjugated
Biotin CSB-PA620882LD01HU MED22 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Gene References into Functions
  1. functional communications between the MED1 subunit and the MED24-containing submodule that mediate estrogen receptor functions and growth of both normal mammary epithelial cells and breast carcinoma cells. PMID: 22331469
  2. Hu-Surf5 encodes three different transcripts, Surf-5a, Surf-5b, and Surf-5c, which result from alternative splicing. PMID: 11891058
  3. This publication also contains human sequence. PMID: 8586415
Subcellular Location
Nucleus.
Protein Families
Mediator complex subunit 22 family
Database Links

HGNC: 11477

OMIM: 185641

KEGG: hsa:6837

STRING: 9606.ENSP00000342343

UniGene: Hs.78354

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