MSTO1 Antibody

Code CSB-PA880106LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA880106LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA880106LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MSTO1 Polyclonal antibody
Uniprot No.
Target Names
MSTO1
Alternative Names
MSTO1 antibody; LST005 antibody; SLTP005 antibody; Protein misato homolog 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein misato homolog 1 protein (1-280AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MSTO1 Antibody (Product code: CSB-PA880106LA01HU) is Non-conjugated. For MSTO1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA880106LB01HU MSTO1 Antibody, HRP conjugated ELISA
FITC CSB-PA880106LC01HU MSTO1 Antibody, FITC conjugated
Biotin CSB-PA880106LD01HU MSTO1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the regulation of mitochondrial distribution and morphology. Required for mitochondrial fusion and mitochondrial network formation.
Gene References into Functions
  1. we have described two unrelated patients with biallelic MSTO1 mutations. Our report provides valuable information on the consequences of MSTO1 mutations for human phenotypes. PMID: 29339779
  2. Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxia PMID: 28544275
  3. Thus, an MSTO1 loss-of-function mutation is associated with a human disorder showing mitochondrial involvement. MSTO1 likely has a physiologically relevant role in mitochondrial morphogenesis by supporting mitochondrial fusion. PMID: 28554942
  4. These results indicated that human Misato has a role(s) in mitochondrial distribution and morphology and that its unregulated expression leads to cell death. PMID: 17349998
Involvement in disease
Myopathy, mitochondrial, and ataxia (MMYAT)
Subcellular Location
Mitochondrion outer membrane. Cytoplasm.
Protein Families
Misato family
Tissue Specificity
Present in all cell lines tested (at protein level). Widely expressed.
Database Links

HGNC: 29678

OMIM: 617619

KEGG: hsa:55154

UniGene: Hs.656547

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