NOA1 Antibody

Code CSB-PA836715LA01HU
Size US$166
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Image
  • Western Blot
    Positive WB detected in: Jurkat whole cell lysate, Hela whole cell lysate, Mouse kidney tissue
    All lanes: NOA1 antibody at 3.4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 79 kDa
    Observed band size: 79 kDa

  • IHC image of CSB-PA836715LA01HU diluted at 1:500 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NOA1 Polyclonal antibody
Uniprot No.
Target Names
NOA1
Alternative Names
NOA1 antibody; C4orf14 antibody; Nitric oxide-associated protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Nitric oxide-associated protein 1 protein (42-174AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NOA1 Antibody (Product code: CSB-PA836715LA01HU) is Non-conjugated. For NOA1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA836715LB01HU NOA1 Antibody, HRP conjugated ELISA
FITC CSB-PA836715LC01HU NOA1 Antibody, FITC conjugated
Biotin CSB-PA836715LD01HU NOA1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:500-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP.
Gene References into Functions
  1. Our results uncovered an unexpected, mandatory detour of NOA1 through the nucleolus before uptake into mitochondria. PMID: 25072814
  2. This study indicates rhat C4orf14 is involved in 28S subunit biogenesis and mtDNA maintenance. PMID: 22447445
  3. The present study suggests a novel function for mAtNOS1 in regulating mitochondrial nitric oxide and calcium and inducing apoptosis of MCF-7 cells PMID: 18456285
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families
TRAFAC class YlqF/YawG GTPase family, NOA1 subfamily
Database Links

HGNC: 28473

OMIM: 614919

KEGG: hsa:84273

STRING: 9606.ENSP00000264230

UniGene: Hs.8715

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