NXNL1 Antibody

1. Study shows that RdCVF acts through binding to Basigin-1 (BSG1), a transmembrane protein expressed specifically by photoreceptors. BSG1 binds to the glucose transporter GLUT1, resulting in increased glucose entry into cones. PMID: 25957687
2. Data suggest a critical role for TXNL6 in MsrA repair of essential lens proteins under oxidative stress conditions and that TXNL6 is important for MsrA defense protection against cataract. PMID: 21079812
3. regulation of the Nucleoredoxin-like genes involves a CRX responsive element that can act as both as a positive regulator of promoter activity and as a modulator of cell-type specificity PMID: 20949100
4. CHX10 regulates RdCVF promoter activity in the inner retina. PMID: 19843539
5. is a truncated thioredoxin-like protein specifically expressed by photoreceptors. The identification of this protein offers new treatment possibilities for retinitis pigmentosa PMID: 15220920
6. RdCVF variants have roles in leber congenital amaurosis PMID: 17249548
7. TXNL6 probably protects retinal cells from photooxidative damage-induced apoptosis via upregulation of NF-kappaB activity PMID: 18474255

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HGNC: 25179

OMIM: 608791

KEGG: hsa:115861

STRING: 9606.ENSP00000305631

UniGene: Hs.661836