NXPH1 Antibody

Code CSB-PA016227LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA016227LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NXPH1 Polyclonal antibody
Uniprot No.
Target Names
NXPH1
Alternative Names
Nbla00697 antibody; Neurexophilin 1 antibody; Neurexophilin-1 antibody; Neurexophilin1 antibody; NPH1 antibody; NXPH 1 antibody; NXPH1 antibody; NXPH1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Neurexophilin-1 protein (22-271AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NXPH1 Antibody (Product code: CSB-PA016227LA01HU) is Non-conjugated. For NXPH1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA016227LB01HU NXPH1 Antibody, HRP conjugated ELISA
FITC CSB-PA016227LC01HU NXPH1 Antibody, FITC conjugated
Biotin CSB-PA016227LD01HU NXPH1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.
Gene References into Functions
  1. identification of SNPs within the IQCJ, NXPH1, PHF17 and MYB genes partly explaining the large interindividual variability observed in plasma triglyceride levels in response to an n-3 fatty acid supplementation PMID: 27160456
  2. A genome-wide association study (GWAS) identified loci associated with the plasma triglyceride (TG) response to omega-3 fatty acid (FA) supplementation in IQCJ, NXPH1, PHF17 and MYB. PMID: 28134766
  3. The role of NXPH1 in in paranoid schizophrenia development in Russians. PMID: 26410934
  4. Rs2349775 (NXPH1) and rs17837965 (CDC42) were associated with diarrhoea and constipation predominant irritable bowel syndrome, respectively, in two independent cohorts. PMID: 24041540
  5. Data indicate that median methylation levels of BCAN, HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis. PMID: 22930747
  6. Data indicate taht candidate genes ACTB, BZW, OCM, MACC1, NXPH1, PRPS1L1, RAC1 and RPA3, which lie within the DFNB90 region, were sequenced and no potentially causal variants were identified. PMID: 21734401
  7. results demonstrate the presence and function of a regulated signaling axis in hematopoiesis centered on NRXN1alpha and its modulation by DAG1 and NXPH1 PMID: 21628410
  8. In rat, neurexophilin 1 forms a very tight complex with neurexin I alpha. PMID: 8699246
  9. In rat, the secreted ligand for alpha-neurexin, neurexophilin 1, is expressed in the postnatal olfactory bulb. PMID: 12141453

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Subcellular Location
Secreted.
Protein Families
Neurexophilin family
Database Links

HGNC: 20693

OMIM: 604639

KEGG: hsa:30010

STRING: 9606.ENSP00000384551

UniGene: Hs.487564

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