PAK6 Antibody

Datasheet

Code	CSB-PA865108ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA865108ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA865108ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PAK6 Polyclonal antibody

Uniprot No.

Q9NQU5

Target Names

PAK6

Alternative Names

CDKN1A activated kinase 6 antibody; EC 2.7.1.37 antibody; p21 activated protein kinase 6 antibody; p21 protein (Cdc42/Rac)-activated kinase 6 antibody; p21(CDKN1A) activated kinase 6 antibody; p21-activated kinase 6 antibody; p21activated kinase 6 antibody; PAK 5 antibody; PAK 6 antibody; PAK-5 antibody; PAK-6 antibody; PAK5 antibody; Pak6 antibody; PAK6_HUMAN antibody; Serine threonine protein kinase PAK 6 antibody; Serine/threonine protein kinase PAK 6 antibody; Serine/threonine protein kinase PAK6 antibody; Serine/threonine-protein kinase PAK 6 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Serine/threonine-protein kinase PAK 6 protein (1-270AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.

Subcellular Location

Cytoplasm. Nucleus. Note=Cotranslocates into nucleus with AR in response to androgen induction.

Protein Families

Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily

Tissue Specificity

Selectively expressed in brain and testis, with lower levels in multiple tissues including prostate and breast.

Database Links

HGNC: 16061

OMIM: 608110

KEGG: hsa:106821730

STRING: 9606.ENSP00000260404

UniGene: Hs.732375

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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