PFDN2 Antibody

Code CSB-PA017813GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PFDN2
Alternative Names
OTTHUMP00000029707 antibody; PFD2 antibody; PFD2_HUMAN antibody; PFDN2 antibody; prefoldin 2 antibody; Prefoldin subunit 2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PFDN2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Gene References into Functions
  1. prefoldin is amplified at 1q23.3-q24.1 in bladder cancer PMID: 23914742
  2. knockdown of PFD2 and PFD5 disrupted prefoldin formation in HTT-expressing cells, resulting in accumulation of aggregates of a pathogenic form of HTT and in induction of cell death. PMID: 23720755
  3. Is part of an RNA polymerase II-associated complex with possible chaperone activity. PMID: 19450687
Subcellular Location
Nucleus. Cytoplasm. Mitochondrion.
Protein Families
Prefoldin subunit beta family
Database Links

HGNC: 8867

OMIM: 613466

KEGG: hsa:5202

STRING: 9606.ENSP00000356989

UniGene: Hs.492516

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