PODN Antibody

Code CSB-PA007057
Size US$100
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Product Details

Uniprot No.
Target Names
PODN
Alternative Names
9430070G18 antibody; LRRGT00160 antibody; MGC24995 antibody; PCAN antibody; Podn antibody; PODN_HUMAN antibody; Podocan antibody; Podocan proteoglycan antibody; RP23 40G2.7 antibody; SLRR5A antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human Podocan.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Negatively regulates cell proliferation and cell migration.
Gene References into Functions
  1. It was apparent that HP upregulates miR-3180-5p, which inhibits the expression of PODN and promotes HBSMC proliferation via the cdk2 signaling pathway. PMID: 27608612
  2. Podocan appears to be a potent negative regulator of the migration and proliferation of vascular smooth muscle cells. PMID: 24043300
  3. PODN was characterized in cultured cells. PMID: 15063725
Subcellular Location
[Isoform 1]: Secreted, extracellular space, extracellular matrix.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.
Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class V subfamily
Tissue Specificity
Kidney, heart, liver, pancreas and vascular smooth muscle cells. Also detected in aortic intima (at protein level).
Database Links

HGNC: 23174

OMIM: 608661

KEGG: hsa:127435

STRING: 9606.ENSP00000308315

UniGene: Hs.586141

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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