PPP1R14B Antibody

Code CSB-PA008762
Size US$119
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Product Details

Uniprot No.
Target Names
PPP1R14B
Alternative Names
PHI 1 antibody; PHI1 antibody; Phospholipase C beta 3 neighboring gene protein antibody; Phospholipase C beta 3 neighbouring gene protein antibody; Phospholipase C-beta-3 neighbouring gene protein antibody; PLCB3N antibody; PNG antibody; PP14B_HUMAN antibody; Ppp1r14b antibody; Protein phosphatase 1 regulatory (inhibitor) subunit 14B antibody; Protein phosphatase 1 regulatory subunit 14B antibody; SOM172 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human PHI-1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated.
Gene References into Functions
  1. Whereas CPI-17 staining was diffuse, PHI-1 was concentrated along the cell membrane in distinct foci. The common tissue distribution but different cellular localization of PHI-1 and CPI-17 suggest distinctive physiological roles for these PP1 inhibitors. PMID: 15083373
  2. PHI-1 participates in regulatory events at the trailing edge of migrating cells and modulates retraction of endothelial and epithelial cells PMID: 15522888
  3. An inhibitory phosphoprotein that inhibits the myosin- and glycogen-associated holoenzyme versions of protein type-1 phosphatase (PP1) as well as the monomeric catalytic subunit of PP1 in multiple tissues. PMID: 10606530
Subcellular Location
Cytoplasm.
Protein Families
PP1 inhibitor family
Tissue Specificity
Ubiquitous. Expressed at low levels.
Database Links

HGNC: 9057

OMIM: 601140

KEGG: hsa:26472

STRING: 9606.ENSP00000310117

UniGene: Hs.523760

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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