PPP6R3 Antibody

Datasheet

Code	CSB-PA020701GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q5H9R7

Target Names

PPP6R3

Alternative Names

C11orf23 antibody; Chromosome 11 open reading frame 23 antibody; KIAA1558 antibody; PP6R3 antibody; PP6R3_HUMAN antibody; PPP6R3 antibody; Protein phosphatase 6 regulatory subunit 3 antibody; SAP190 antibody; SAPL antibody; SAPLa antibody; SAPS domain family member 3 antibody; SAPS domain family; member 3 antibody; Serine/threonine-protein phosphatase 6 regulatory subunit 3 antibody; Sporulation induced transcript 4 associated protein SAPL antibody; Sporulation-induced transcript 4-associated protein SAPL antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human SAPS3

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance.

Gene References into Functions

Results from a study on gene expression variability markers in early-stage human embryos shows that PPP6R3 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
we found a DPP9-PPP6R3 fusion transcript in one tumor showing a matching genomic 11;19-translocation. Another tumor had a rearrangement of DPP9 with PLIN3. Both rearrangements were associated with diminished expression of the 3' end of DPP9 corresponding to the breakpoints identified by RNA-seq. PMID: 28893231
Molecular analyses revealed the presence and amplification of the novel PPPR6-USP6 gene fusion, which resulted in USP6 mRNA transcriptional upregulation. These findings further support the oncogenic role of the USP6 protease in mesenchymal neoplasia and expand the biologic potential of Nodular fasciitis PMID: 27113271

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

SAPS family

Tissue Specificity

Expressed in skeletal muscle, placenta, heart, pancreas, testis, brain, lung, liver, kidney, spleen, thymus, prostate, small intestine, colon and leukocytes.

Database Links

HGNC: 1173

OMIM: 610879

KEGG: hsa:55291

STRING: 9606.ENSP00000377390

UniGene: Hs.503022

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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